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The Korean Journal of Internal Medicine ; : 236-240, 2014.
Article in English | WPRIM | ID: wpr-105987

ABSTRACT

Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivity myocarditis that was probably triggered by amoxicillin and that resolved completely with heart failure management as well as discontinuation of the drug. A 68-year-old woman presented with acute chest pain mimicking acute coronary syndromes, but the coronary angiography was normal. A recent history of taking medications, skin rash, and peripheral eosinophilia suggested a diagnosis of hypersensitivity myocarditis, which was confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.


Subject(s)
Aged , Female , Humans , Amoxicillin/adverse effects , Anti-Bacterial Agents/adverse effects , Biopsy , Drug Hypersensitivity/diagnosis , Electrocardiography , Glucocorticoids/therapeutic use , Magnetic Resonance Imaging , Myocarditis/chemically induced , Myocardium/pathology , Predictive Value of Tests , Prednisolone/therapeutic use , Risk Factors , Treatment Outcome
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